Name: Dr. Y.V. Madhavi Associate Professor yvmadhavi@niperhyd.ac.in yssmadhavi@gmail.com +91 40 23074750 Extn- 2031 Google Scholar Citations https://scholar.google.com/citations?hl=en&user=8wCy9L4AAAAJ

ADDRESS, ROOM NO

Department of Process Chemistry
Room. No. 17, NIPER Hyderabad
Balanagar, Hyderabad-500037, TS, INDIA

QUALIFICATION: (REVERSE CHRONOLOGICAL ORDER)

• Ph.D. (2002–2007), CSIR-IICT, Hyderabad, India
• M.Sc (1996-1998), Osmania University, India
• B.Sc (1993–1996), Osmania University, India

EXPERIENCE

• Associate Professor (Jan 2025 – till date), NIPER-Hyderabad
• Assistant Professor (August 2013 – Dec 2024), NIPER-Hyderabad
• PDF-Asst.Manager IPDO Dr.Reddy,s (-August 2007-July 2013)
• GSK project -IICT (2020-2022)

COURSES HANDLING(PHD/M.PHARM)

• PhD: Principles Of Peptide Chemistry -(MC-810); Technologies for Green Chemistry( PT-710);
• M.Pharm, M.Tech: Industrial Process and scale up techniques (PT-510)
• Logic In Organic Synthesis(MC-520)
• Synthetic Aspects of Process Chemistry(PT-560)
• Topics Relevant To Drugs And Pharmaceutical Industry(PT-610),
• Synthetic Aspects of Process Chemistry(PT-560)
• General Laboratory Experience(LG-510, LS-610)

PHD STUDENTS/MASTERS STUDENTS

• M.S (Pharm) Awarded: 40
• PhD Awarded: 7
• MS (Pharm) Ongoing: 7
• PhD Ongoing: 5

AWARDS / HONOURS

• Associate Fellow of the APAS for the Telangana and Andhra Pradesh States

RESEARCH AREAS/INTEREST

• Process Development of API’s & Intermediates
• Development of new heterocyclic analogues as antimicrobial agents targeting MtCA, DprE1, MmpL3 and DNA Gyrase
• Structure based design, synthesis and evaluation of new anti-cancer and anti-infective agents,
• Total synthesis of biologically active Natural Products
• Development of new methodologies.
• Multi-component and cascade reactions
• Development of alternative sustainable greener methods in pharmaceutical chemistry
• Exploration of new synthetic methodologies and studying their mechanisms
• Metal free photocatalyzed synthesis of NCEs.

FELLOWSHIPS/GRANTS

• SRF (2004–2007) in Chemical Sciences, CSIR, India
• JRF (2002–2004) in Chemical Sciences, CSIR, India

SPONSORED PROJECTS

Sl. No	Title of the Project	Funding Organization	Role	Amount (INR)	Status
1	Development of scalable route for the manufacture of Prussian Blue insoluble of pharmaceutical grade, an FDA approved decorporation drug	LSRB	Principal Investigator (PI)	₹49,76,640/- (2019)	Completed
2	Development of Scalable, safe and cost effective process for the API of Umifenovir (Arbidol), a promising repurposed drug for COVID-19 in India	NRDC	Principal Investigator (PI)	₹10,00,000/- (2021)	Completed
3	Novel synthetic process and formulation development of Eliglustat tartrate	DST (SERB)	Principal Investigator (PI)	₹41,88,542/- (2023)	In Progress
4	Design, synthesis, and development of scalable route towards novel compounds based on the hybrid structure of Hymenialdisins and Paullones and a novel scaffold derived from Variolins	Ministry of Earth Sciences	Co-Principal Investigator (Co-PI)	₹45,00,000/- (2016–2019)	Completed
5	Synthesis and therapeutic evaluation of new LpxC inhibitors as potent antibacterial agents	DST (SERB)	Co-Principal Investigator (Co-PI)	₹43,00,000/- (2017–2020)	Completed

PUBLICATIONS / BOOK CHAPTERS

• Click here

PATENTS

1. An improved synthesis for alpha-bromination of sulphonamide substituted aryl-alkyl ketones H.M. Meshram.; A.V. Madhavi.; B. Eshwaraiah. J.S. YadavIndian Patent No: 259/DEL/03. dated 10/3/2003
2. Process for the synthesis of bis (substituted-4-quinolyl)-disulphides. Meshram, H. M.; Premalatha, K.; A. V. Madhavi.; Eeshwaraiah, B. J. S. Yadav. Patent no: U S 6777553. Date of grant: 17-8-2004. Indian Patent: 254/DEL/03, US [6777553] Japan [2004-570090] Germany [10394213.0] South Africa [2005-07913]
3. “Preparation of Valganciclovir and its salts" Reddy, P. P.; Anand, R. V.; Babu, I.; Babu, K. S.; Reddy, G. M.; Krishna, J.; Srinivas, P.; Madhavi, Y. V.; Haldar, P.; Krishna, V.; Rao, P. N.; Ravindra, V.; Satyanarayana, K.; Raju, V. V. N. K. V.; Suchitra, S. K.; Sakthivel, S.; Medisetti, R. K. V.; Manudhane, K. S. PCT Patent Application WO 2010/036904 A2
4. “Asenapine Maleate: Processes for its preparation and pharmaceutically acceptable dosage forms thereof” Srinivas, K.; Srinivas, P.; Madhavi,Y. V.; Krishna Vinigari.; Rao, P.N.; Rajeshwar Reddy, S. Patent Application WO2011159903A2 Patent granted in July15, 2014. Patent No. 8779161
5. Substituted Isoxazole compounds as antibacterial agents, Indian Patent Application no: 202141001125, TEMP/E-1/1172/2021-CHE
6. Substituted pyrazole compounds as antibacterial agents, Indian Patent Application no: 202141007157, TEMP/E1/7780/2021-CHE

INVITED TALKS

Will update very soon

ADDITIONAL RESPONSIBILITIES

Girls hostel Warden, Co-Chair, SPC-I

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