NIPER S.A.S Nagar was the 1st institute established in the year 1998. Later Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Govt. of India established 6 new NIPERs across the country in the year 2007 including NIPER-Hyderabad which started functioning from 19th October 2007, from the premises of erstwhile R&D Centre of IDPL, Balanagar, Hyderabad.