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His area of research is to identify and develop specific methodologies and technologies that help in mitochondria-based drug discovery, discovering relevant therapeutic peptides for specific diseases using in silico tolls, uncovering new chemical entities (NCEs) while screening through in vitro and in vivo assay systems and cancer genomics vis-à-vis cancer (i.e. prostate and breast) and neurodegenerative (i.e. Alzheimer’s), and viral diseases.
Full Profile
Dr. Priyanka Bajaj’s group has particular interest in green chemistry to make our pharmaceutical and fine chemical industry and industrial products more environmentally friendly and affordable for everyone. Her research mainly focuses on developing green biocatalytic processes and enzymes for complex synthetic chemistry challenges mainly focusing on synthesis of chiral compounds of pharmaceutical importance. The enzymes are studied in detail for their structure activity relationship and engineered using the techniques of directed evolution. The libraries of various substrates and enzymes are further screened in high throughput mode using LC/MS, GC/MS and UV-Vis spectrophotometry and upscale and downscale processes are optimized. The group is working on exploring wide range of enzymes including Aldehyde dehydrogenases (ALDHs), Myoglobin, P450s and others.
Her Research Interest includes the below
