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Publications in 2021

Publications are the primary method for reporting and long-term documentation of the research conducted at the NIPER-Hyderabad. Here the list of publications published in year wise...

  1. PooladandaV, Thatikonda S, Godugu C (2020). The current understanding and potential therapeutic options to combat COVID-19. Life sciences 254: 117765.
  2. Chilvery S, Bansod S, Saifi MA, Godugu C (2020). Piperlongumine attenuates bile duct ligation-induced liver fibrosis in mice via inhibition of TGF-β1/Smad and EMT pathways. International Immunopharmacology 88: 106909.
  3. Bansod S, Doijad N, Godugu C (2020). Berberine attenuates severity of chronic pancreatitis and fibrosis via AMPK-mediated inhibition of TGF-β1/Smadsignaling and M2 polarization. Toxicology and Applied Pharmacology 403: 115162.
  4. Manasa KL, Thatikonda S, Sigalapalli DK, Sagar A,Kiranmai G,Kalle AM, Alvala M, Godugu C, Narayana N,Babu BN (2020). Design and Synthesis of β-carboline linked aryl sulfonyl piperazine derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability. Bioorganic Chemistry101: 103983.
  5. Goud NS, Pooladanda V, Chandra KM, Souky PL, Alvala R, Kumar P,Chandana N, Bharath RS, Qureshi IA, Godugu C, Alvala M (2020). Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies. Bioorganic Chemistry 102: 104125.
  6. Gera S, PooladandaV, Godugu C, SwamyChalla V, Wankar J, Dodoala S,Sampathi S (2020). Rutinnanosuspension for potential management of osteoporosis: effect of particle size reduction on oral bioavailability, in vitro and in vivo activity. Pharmaceutical development and technology 25(8): 971-988.
  7. Sravani S, Saifi MA, Godugu C (2020). Riociguat ameliorates kidney injury and fibrosis in an animal model. Biochemical and Biophysical Research Communications 530(4): 706-712.
  8. Bireddy SR, Konkala VS, Godugu C, Dubey PK (2020). A Review on the Synthesis and Biological Studies of 2, 4-Thiazolidinedione Derivatives. Mini-Reviews in Organic Chemistry 17(8): 958-974.
  9. Santosh Kumar Sahoo, Bandela Rani, Nikhil Baliram Gaikwad, Mohammad Naiyaz Ahmad, Grace Kaul, Manjulika Shukla, Srinivas Nanduri, Arunava Dasgupta, Sidharth Chopra and Venkata Madhavi Yaddanapudi*, Synthesis and structure activity relationship of new chalcone linked 5-phenyl-3-isoxazolecarboxylic acid methyl ester potentially active against drug resistant Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. I.F: 5.57
  10. Malasala, S.; Polomoni, A.; Ahmad, N.; Shukla, M.; Kaul, G.; Dasgupta, A.; Chopra, S.; Nanduri, S. Structure Based Design, Synthesis and Evaluation of New Thienopyrimidine Derivatives as Anti-Bacterial Agents. Journal of Molecular Structure 1234, 130168.
  11. Akunuri, R.; Vadakattu, M.; Bujji, S.; Veerareddy, V.; Madhavi, Y. V.; Nanduri, S. Fused-Azepinones: Emerging Scaffolds of Medicinal Importance. European journal of medicinal chemistry 2021, 220, 113445.
  12. Malasala, S.; Polomoni, A.; Chelli, S. M.; Kar, S.; Madhavi, Y. V.; Nanduri, S. A Microwave-Assisted Copper-Mediated Tandem Approach for Fused Quinazoline Derivatives. Organic & biomolecular chemistry 2021, 19 (8), 1854–1859.
  13. Gatadi, S.; Madhavi, Y. V.; Nanduri, S. Nanoparticle Drug Conjugates Treating Microbial and Viral Infections: A Review. Journal of Molecular Structure 2021, 1228, 129750.
  14. Cherix A, Sonti R, Lanz B, Lei H. In Vivo Metabolism of [1,6- 13C2]Glucose Reveals Distinct Neuroenergetic Functionality between Mouse Hippocampus and Hypothalamus Metabolites. 2021; 11, 50.
  15. Priyanka N. Makhal, Arijit Nandi, Venkata Rao Kaki. Insights into the recent synthetic advances of organoselenium compounds. ChemistrySelect, 2021, 6, 663 - 679.
  16. Nikhil Baliram Gaikwad.; Pathan Afroz.; Mohammad Naiyaz Ahmad.; Grace Kaul.; Manjulika Shukla.; Srinivas Nanduri.;Arunava Dasgupta.;, Sidharth Chopra.;Venkata Madhavi Yaddanapudi. Design, synthesis, in vitro and in silico evaluation of new 3-phenyl-4,5-dihydroisoxazole-5-carboxamides active against drug-resistant mycobacterium tuberculosis Journal Of Molecular Structure, 2021, 129545
  17. Baijayantimala Swain.; Kamtam Aashrita.; Priti Singh.; Andrea Angeli.; Abhay Kothari.; Dilep K. Sigalepalli.; Venkata M. Yaddanapudi.; Claudia T. Supuran.; Mohammad Arifuddin. Design and Synthesis of benzenesulfonamide-linked imido[2,1-b][1,3,4]thiadiazole derivatives as carbonic anhydrase I and II inhibitors. Arch Pharm DphG, 2021 https://doi.org/10.1002/ardp.202100028
  18. Dandekar MP, Diaz AP, Rahman Z, Silva RH, Nahas Z, Aaronson S, Selvaraj S, Fenoy AJ, Sanches M, Soares JC, Riva-Posse P, Quevedo J. A narrative review on invasive brain stimulation for treatment-resistant depression. Braz J Psychiatry, 44(3):317-330. (IF: 6.33)
  19. Rahman Z, Dandekar MP (2021). Crosstalk between gut microbiome and immunology in the management of ischemic brain injury. Journal of Neuroimmunology 353, 577498.
  20. Rahman Z, Bazaz MR, Pasam T, Kumar M, Dandekar MP (2021). Importance of biological clock epigenetics in the manifestation of polycystic ovary syndrome. Biological sciences, 2021 (01), 67-81.
  21. Pooja Reddy M, Priyanka Makhal, Venkata Rao Kaki. Potential herbal drugs and phytochemicals to minimize the risk of COVID-19: A review. J. Pharmcogn. Phytochem. 2021, 10, 670-675.
  22. Baby, S.; Durgesh, G. V.; Shankaraiah, N. Unraveling KDM4 histone demethylase inhibitors for cancer therapy; Drug Discovery Today 2021, 26, 1841-1856
  23. John, S.; Gulati, S.; Shankaraiah, N. Recent Advances in Multi-component Reactions and their Mechanistic Insights: A Triennium Review; Org. Chem. Front., 2021, 8, 4237–4287
  24. Bora, D.; Galla, M. S.; Shankaraiah, N. The Role of Sulphonamides and N-Sulphonyl Ketimines/Aldimines as Directing Groups in the Field of C-H Activation; Chem. Asian J. 2021, 16, 1661–1684
  25. Soni, J. P.; Yeole. Y.; Shankaraiah. N. β-Carboline Based Molecular Hybrids as Anticancer Agents: A Brief Sketch; RSC Med. Chem. 2021, 12, 730–750
  26. Application of transition metal-catalyzed C-H activation strategies in the synthesis and functionalization of β-carbolines; Riyazahmed, K. S.; Bora, D.; Shankaraiah, N. Asian J. Org. Chem., 2021, 10, 1050–1066
  27. TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines: facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline; Sathish, M.; Sakla, A. P.; Nachtigall, F. M.; Santos, L. S.; Shankaraiah, N. RSC Adv., 2021, 11, 16537
  28. Microwave-assisted multicomponent reactions in heterocyclic chemistry and mechanistic aspects; Gulati, S.; John, S. E.; Shankaraiah, N. Beilstein J. Org. Chem., 2021, 17, 819–865
  29. Cyclodesulfurization: An Enabling Protocol for Synthesis of Various Heterocycles; Kadagathur, M.; Shaikh, A. S.; Jadhav, G.; Sigalapalli, D. K.; Shankaraiah, N.; Tangellamudi, N.D. ChemistrySelect 2021, 6, 2621-2640
  30. Synthesis and in vitro Cytotoxicity Evaluation of Phenanthrene Linked 2, 4-Thiazolidinediones as Potential Anticancer Agents; Yadav, U.; Vanjari, Y.; Laxmikeshav, K.; Tokala, R.; Niggula, P. K.; Kumar, M.; Talla, V.; Kamal, A.; Shankaraiah, N. Anti-cancer Agents in Med. Chem., 2021, 21, 1127–1140
  31. The Riveting Chemistry of Poly-Aza-Heterocycles Employing Microwave Technique: A Decade Review; Soni, J. P.; Joshi, S. V.; Chemitikanti, K. S.; Shankaraiah, N. Eur. J. Org. Chem., 2021, 1476-1490
  32. Structural Insights of Oxindole based Kinase Inhibitors as Anticancer Agents: Recent Advances; Dhokne, P.; Sakla, A. P.; Shankaraiah. N. Eur. J. Med. Chem. 2021, 216, 113334
  33. Cinnamide Derived Pyrimidine-Benzimidazole Hybrids as Tubulin Inhibitors: Synthesis, In silico and Cell Growth Inhibition Studies; Sana, S.; Reddy, V. G.; Reddy, T. S.; Tokala, R.; Bhargava, S. K.; Shankaraiah, N. Bioorg. Chem. 2021, 110, 104765
  34. Anticancer potential of spirocompounds in medicinal chemistry: A pentennial expedition; Bora, D.; Kushal, A. Shankaraiah, N. Eur. J. Med. Chem. 2021, 215, 113263
  35. Synthesis and medicinal chemistry of azepinoindolones: A look back to leap forward; Kadagathur, M.; Patra, S.; Sigalapalli, D. K.; Shankaraiah, N.; Tangellamudi, N. D. Org. Biomol. Chem., 2021, 19, 738–764
  36. Syntheses and applications of spirocyclopropyl oxindoles: A decade review; Sakla, A. P.; Kansal, P.; Shankaraiah, N. Eur. J. Org. Chem., 2021, 757-772
  37. Development of β-Carboline-Benzothiazole Congeners via Carboxamide Formation as Cytotoxic Agents: Intercalative Topoisomerase IIα Inhibition and Apoptosis Induction; Tokala, R.; Mahajan, S.; Kiranmai, G.; Sigalapalli, D. K.; Sana, S.; Stephy Elza John, Narayana Nagesh Shankaraiah, N.; Bioorg. Chem., 2021, 106, 104481
  38. Kumar, S.; Nunewar, S.; Usama, K.S.; Kanchupalli, V.* “Rh(III)-Catalyzed [3+2] Annulation & C-H alkenylation of Indoles with 1,3-Diynes via C-H activation” Eur. J. Org. Chem. 2021, 15, 2223-2229.
  39. Nunewar, S.; Kumar, S.; Talakola, S.; Nanduri, S.; Kanchupalli, V. “Co(III), Rh(III) & Ir(III)-Catalyzed Direct C–H Alkylation/ Alkenylation/ Arylation with carbene precursors” Chem Asian J. 2021, 16, 443-459.
  40. Kumar, S.; Nunewar, S.; Oluguttula, S.; Nanduri, S.; Kanchupalli, V. “Recent advances in Rh(III)/Ir(III)-catalyzed C-H functionalization/annulation via carbene migratory insertion:” Org. Biomol. Chem., 2021, 19, 1438-1458.
  41. Nunewar, S.; Kumar, S.; Pandhare. H; Nanduri, S.; Kanchupalli, V. “Rh(III)-Catalyzed Chemodivergent Annulations between Indoles and Iodonium Carbenes: A Rapid Access to Tricyclic and Tetracyclic N-Heterocylces” Org. Lett. 2021, (https://doi.org/10.1021/acs.orglett.1c01167)
  42. Sherkhane, B.; Chayanika, G.; Sood, A.; Khatri, D. K.; Singh, S. B. Mitochondrial Remodelling a Vicious Cycle in Diabetic Complications. Mol. Biol. Rep. 2021. DoI: https://doi.org/10.1007/s11033-021-06408-8.
  43. Khan, I.; Preeti, K.; Fernandes, V.; Khatri, D. K.; Singh, S. B. Role of MicroRNAs, Aptamers in Neuroinflammation and Neurodegenerative Disorders. Cell. Mol. Neurobiol. 2021, 1–21. DoI https://doi.org/10.1007/s10571-021-01093-4
  44. Kadbhane A, Patel M, Srivastava S, Singh PK, Madan J, Singh SB, Khatri DK. Perspective Insights and Application of Exosomes as a Novel Tool against Neurodegenerative Disorders: An Expository Appraisal. J. Drug Deliv. Sci. Technol. 2021, 102526. https://doi.org/10.1016/j.jddst.2021.102526
  45. Khatri, D. K.; Kadbhane, A.; Patel, M.; Nene, S.; Atmakuri, S.; Srivastava, S.; Singh, S. B. Gauging the Role and Impact of Drug Interactions and Repurposing in Neurodegenerative Disorders. Curr. Res. Pharmacol. Drug Discov. 2021, 2, 100022. DoI: https://doi.org/10.1016/j.crphar.2021.100022
  46. Nellaiappan K, Kumari P, Khatri DK, Singh SB. Diabetic Complications: An Update on Pathobiology and Therapeutic Strategies. Curr. Diabetes Rev. 2021. DOI: 10.2174/1573399817666210309104203
  47. Arruri, V. K.; Gundu, C.; Khan, I.; Khatri, D. K.; Singh, S. B. PARP Overactivation in Neurological Disorders. Mol. Biol. Rep. 2021, 1–9. DoI: https://doi.org/10.1007/s11033-021-06285-1
  48. Modani, S.; Tomar, D.; Tangirala, S.; Sriram, A.; Mehra, N. K.; Kumar, R.; Khatri, D. K.; Singh, P. K. An Updated Review on Exosomes: Biosynthesis to Clinical Applications. J. Drug Target. 2021, 1–16. DoI: https://doi.org/10.1080/1061186X.2021.1894436
  49. Arruri, V. K.; Gundu, C.; Kalvala, A. K.; Sherkhane, B.; Khatri, D. K.; Singh, S. B. Carvacrol Abates NLRP3 Inflammasome Activation by Augmenting Keap1/Nrf-2/P62 Directed Autophagy and Mitochondrial Quality Control in Neuropathic Pain. Nutr. Neurosci. 2021, 1–16. DoI: https://doi.org/10.1080/1028415X.2021.1892985
  50. Sharma, N.; Modak, C.; Singh, P. K.; Kumar, R.; Khatri, D.; Singh, S. B. Underscoring the Immense Potential of Chitosan in Fighting a Wide Spectrum of Viruses: A Plausible Molecule against SARS-CoV-2? Int. J. Biol. Macromol. 2021. DoI: https://doi.org/10.1016/j.ijbiomac.2021.02.090
  51. Vivek Dhiman, Ankit Balhara, Saranjit Singh, Shristy Tiwari, Samanthula Gananadhamu, MVN Kumar Talluri, Characterization of stress degradation products of nintedanib by UPLC, UHPLC-Q-TOF/MS/MS and NMR: Evidence of a degradation product with a structure alert for mutagenicity, Journal of pharmaceutical and biomedical analysis, 2021, 199, 114037.
  52. Singh S, Sharma N, Bansal A, Kanojia N, Sethi S, Madan J, Sodhi RK. Apoptosis modulating nanochemotherapeutics in the treatment of cancer: Recent progress and advances. Clinical Perspectives and Targeted Therapies in Apoptosis, 2021; 153-207, Elsevier.
  53. Sodhi RK, Grewal AK, Madan J, Jhajj TGS, Kumar R. Recent approaches to target apoptosis in neurological disorders. Clinical Perspectives and Targeted Therapies in Apoptosis, 2021; 217-283. Elsevier.
  54. Chahal SK, Sodhi RK, Madan J, Singh Y. Diabetic neuropathy: Pathophysiology and therapeutic options. In: Diabetes and Diabetic Complications. Nova Science Publishers, Inc. 2021; 99-122.
  55. Bajwa N, Singh PA, Sainaga Jyothi VGS, Sodhi RK, Baldi A, Sardana S, Chandra R, Madan J. Chronicle of Nanomicelles in Drug Delivery: From Bench to Bedside. Nanomaterials: Evolution and Advancement (Part 1), 2021, 161-210.
  56. Hirawat R, Saifi MA, Godugu C (2021). Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications. Life Sciences 267: 118923.
  57. Pooladanda V, Thatikonda S, Sunnapu O, Tiwary S, Vemula PK, Talluri MK, Godugu C (2021). iRGD conjugated nimbolide liposomes protect against endotoxin induced acute respiratory distress syndrome. Nanomedicine: Nanotechnology, Biology and Medicine 33: 102351.
  58. Bansod S, Chilvery S, Saifi MA, Das TJ, Tag H, Godugu C (2021). Borneol protects against cerulein‐induced oxidative stress and inflammation in acute pancreatitis mice model. Environmental Toxicology 36(4): 530-539
  59. Rahman Z, Bazaz MR, Devabattula G, Khan MA, Godugu C (2021). Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer. Journal of biochemical and molecular toxicology 35(3): e22674.
  60. Anchi P, Swamy V, Godugu C (2021). Nimbolide exerts protective effects in complete Freund's adjuvant induced inflammatory arthritis via abrogation of STAT-3/NF-κB/Notch-1 signaling. Life Sciences 266: 118911.
  61. Saifi MA, Poduri R, Godugu C (2021). Nanomedicine: implications of nanotoxicology. Drug Discovery and Development: From Targets and Molecules to Medicines 393-415.
  62. Gangadevi V, Thatikonda S, Pooladanda V, Devabattula G, Godugu C (2021). Selenium nanoparticles produce a beneficial effect in psoriasis by reducing epidermal hyperproliferation and inflammation. Journal of Nanobiotechnology 19(1): 1-19.
  63. Pooladanda V, Thatikonda S, Muvvala SP, Devabattula G, Godugu C (2021). BRD4 targeting nanotherapy prevents lipopolysaccharide induced acute respiratory distress syndrome. International Journal of Pharmaceutics 601: 120536.
  64. Ali SA, Saifi MA, Pulivendala G, Godugu C, Talla V (2021). Ferulic acid ameliorates the progression of pulmonary fibrosis via inhibition of TGF-β/smad signalling. Food and Chemical Toxicology 149: 111980.
  65. Saifi MA, Annaldas S, Godugu C (2021). A direct thrombin inhibitor, dabigatran etexilate protects from renal fibrosis by inhibiting protease activated receptor-1. European Journal of Pharmacology 893: 173838.
  66. Sigalapalli DK, Pooladanda V, Kadagathur M, Guggilapu SD, Uppu JL, Godugu C, Bathini NB, Tangellamudi ND (2021). Novel chromenyl-based 2-iminothiazolidin-4-one derivatives as tubulin polymerization inhibitors: Design, synthesis, biological evaluation and molecular modelling studies. Journal of Molecular Structure 1225: 128847.
  67. Bansod S, Godugu C (2021). Nimbolide ameliorates pancreatic inflammation and apoptosis by modulating NF-κB/SIRT1 and apoptosis signaling in acute pancreatitis model. International Immunopharmacology 90: 107246
  68. Amey Kadbhane, Monica Patel, Saurabh Srivastava, Pankaj Kumar Singh, Jitender Madan, Shashi Bala Singh, Dharmender Khatri. Perspective Insights of Schematically Manoeuvred Extracellular Vesicles as a Novel Tool against Neurodegenerative Disorders: An Expository Appraisal. Journal of Drug Delivery Science and Technology, Accepted April, 2021, [Impact factor: 2.734].
  69. Shweta Nene, Saurabh Shah, Nagarjun Rangaraj, Neelesh Kumar Mehra, Pankaj Kumar Singh, Saurabh Srivastava. Lipid based nanocarriers: A novel paradigm for topical antifungal therapy. J Drug Deliv Sci Technol, Volume 62, April 2021, 102397. [Impact factor: 2.73].
  70. Mehra NK. Dendrimers in Nanomedicines. Cutting Edge Magazine. April 2021. Page 15.
  71. Identification and Evaluation of Apoptosis-Inducing Activity of Ipomone from Ipomoea nil: A Novel, Unusual Bicyclo- [3.2.1] Octanone Containing Gibberic Acid Diterpenoid Bharat Goel; Essha Chatterjee; Biswajit Dey; Nancy Tripathi; Nivedita Bhardwaj; Arun Khattri; Santosh Kumar Guru; Shreyans K. Jain. ACS Omega 2021, 6, 8253−8260
  72. Targeting eosinophils in respiratory diseases: Biological axis, emerging therapeutics and treatment modalities. Li-Yen Lee, Geena Suet Yin Hew, Meenu Mehta, Shakti D. Shukla, Saurabh Satija, Navneet Khurana, Krishnan Anand, Harish Dureja, Sachin Kumar Singh, Vijay Mishra, Pankaj Kumar Singh, Monica Gulati, Parteek Prasher, Alaa A.A. Aljabali, Murtaza M. Tambuwala, Lakshmi Thangavelu, Jithendra Panneerselvam, Gaurav Gupta, Flavia C. Zacconi, Madhur Shastri, Niraj Kumar Jha, Dikaia Xenaki, Ronan MacLoughlin, Brian G. Oliver, Dinesh Kumar Chellappan, Kamal Dua. Life Sci., Volume 267, 15 February 2021, 118973, [Impact factor: 3.647].
  73. Saurabh Shah, Nagarjun Rangaraj, Shashi Bala Singh and Saurabh Srivastava*, Exploring the Unexplored Avenues of Surface charge in Nano-medicine. Colloids and Interface Science Communications, Vol. 42, 100406, 2021
  74. Aditi Bhat, Harshita Dalvi, Harsha Jain, Nagarjun Rangaraj, Shashi Bala Singh, Saurabh Srivastava* Perspective Insights of Repurposing the Pleiotropic Efficacy of Statins in Neurodegenerative Disorders: An Expository Appraisal Current Research in Pharmacology and Drug Discovery, Vol 02, 100012, 2021
  75. Stephy Elza John, Ramya Tokala, Venkata Rao Kaki, Nagula Shankaraiah. Expedition to Phenanthrene Nucleus: A Two- decade Research on Bench. Asian J. Org. Chem., 2021, 10(8), 2105-2136
  76. Minakshi A Meshram, Utkarsha O Bhise, Priyanka N Makhal, Venkata Rao Kaki. Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR. Eur. J. Med. Chem. 2021, 225, 113804.
  77. Sakla, A. P.; Panda, B.; Laxmikeshav, K.; Soni, J. P.; Bhandari, S.; Godugu, C.; Shankaraiah, N. Dithiocarbamation of spiro-aziridine oxindoles: a facile access to C3-functionalised 3-thiooxindoles as apoptosis inducing agents; Org. Biomol. Chem., 2021, 19, 10622–10634
  78. Soni, J. P.; Kadagathur, M.; Shankaraiah, N. Recent updates on azido-reductive cyclization approaches: syntheses of aza-heterocyclic frameworks; Asian J. Org. Chem., 2021, 10, 3186-3200
  79. Bora, D.; Dannarm, S. R.; John, S. E.; Sana, S.; Sonti, R.; Shankaraiah, N. Regioselective ortho-sulphonamidation of β-carbolines: intrinsic directing property of β-carbolines and their photophysical studies; Asian J. Org. Chem., 2021, 10, 3384-3389
  80. Namballa, H. K.; Anchi, P.; Manasa, K. L.; Soni, J. P.; Godugu, C.; Shankaraiah, N. β-Carboline tethered cinnamoyl 2-aminobenzamides as class I selective HDAC inhibitors: Design, synthesis, antiproliferative activity and modelling studies; Kamal, A. Bioorg. Chem. 2021, 117, 105461
  81. Sigalapalli, D. K.; Kiranmai, G.; Tokala, R.; Tripura, C.; Ambatwar, R.; Nunewar, S. N.; Kadagathur, M.; Shankaraiah, N.; Nagesh, N.; Babu, B. N.; Tangellamudi, N. D. Targeting Tubulin Polymerization and DNA Binding of 4-Thiazolidinone-umbelliferone Hybrids: Synthesis and Cytotoxicity Evaluation; New J. Chem., 2021, 45, 18908-18923
  82. G. V. Durgesh.; Kadagathur, M.; Shankaraiah, N. Stereoselective Aldol and Conjugate Addition Reactions Mediated by Proline-Based Catalysts and Its Analogues: A Concise Review; Eur. J. Org. Chem., 2021, 37, 5288-5311
  83. Laxmikeshav, K.; Kumari, P.; Shankaraiah, N. Expedition of sulfur-containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update; Med. Res. Rev., 2021, 42, 513-575
  84. Saeed, R.; Sakla, A. P.; Shankaraiah, N. An update on the progress of cycloaddition reactions of 3-methyleneindolinones in the past decade: versatile approaches to spirooxindoles; Org. Biomol. Chem., 2021, 19, 7768–7791
  85. Madhumanti Barman , Sonam Kamble , Sonti Roy , Vasundhra Bhandari, Siva Singothu, Debabrata Dandasena, Akash Suresh, Paresh Sharma. Antitheilerial Activity of the Anticancer Histone Deacetylase Inhibitors. Frontiers in Microbiology. 2021, 12, 759817.
  86. Dandekar MP, Yin X, Peng T, Devaraj S, Morales R, McPherson DD, Huang S (2022). Repetitive xenon treatment improves post-stroke sensorimotor and neuropsychiatric dysfunction. Journal of Affective Disorder. 301:315-330. (IF: 6.53)
  87. Bazaz MR, Balasubramanian R, Monroy-Jaramillo N, Dandekar MP (2021). Linking the triad of telomere length, inflammation and gut dysbiosis in the manifestation of depression. ACS Chem Neurosci, 12(19):3516-3526.
  88. Singh A, Dandekar MP (2021). A Review on Preclinical Models of Ischemic Stroke: Insights Into the Pathomechanisms and New Treatment Strategies. Curr Neuropharmacol. doi: 10.2174/1570159X19666210907092928.
  89. Ambekar, T.; Pawar, J.; Rathod, R.; Patel, M.; Fernandes, V.; Kumar, R.; Singh, S. B.; Khatri, D. Mitochondrial Quality Control: Epigenetic Signatures and Therapeutic Strategies. Neurochem. Int. 2021, 105095.
  90. Maji, I.; Mahajan, S.; Sriram, A.; Medtiya, P.; Vasave, R.; Khatri, D. K.; Kumar, R.; Singh, S. B.; Madan, J.; Singh, P. K. Solid Self Emulsifying Drug Delivery System: Superior Mode for Oral Delivery of Hydrophobic Cargos. J. Control. Release 2021.
  91. KHATRI, D. K.; Patidar, V.; Shah, S.; Kumar, R.; Singh, P. K.; Singh, S. B.; Khatri, D. K. A Molecular Insight of Inflammatory Cascades in Rheumatoid Arthritis and Anti-Arthritic Potential of Phytoconstituents. Mol. Biol. Rep. 2021. https://doi.org/10.1007/s11033-021-06986-7.
  92. KHATRI, D. K.; Sood, A.; Preeti, K.; Fernandes, V.; Khatri, D. K.; Singh, S. B. Glia: A Major Player in Glutamate GABA Dysregulation‐mediated Neurodegeneration. J. Neurosci. Res. 2021. https://doi.org/10.1002/jnr.24977.
  93. Dondulkar, A.; Akojwar, N.; Katta, C.; Khatri, D. K.; Mehra, N. K.; Singh, S. B.; Madan, J. Inhalable Polymeric Micro and Nano-Immunoadjuvants for Developing Therapeutic Vaccines in the Treatment of Non-Small Cell Lung Cancer. 2021, 27. https://doi.org/10.2174/1381612827666211104155604.
  94. Famta, P.; Shah, S.; Khatri, D. K.; Guru, S. K.; Singh, S. B.; Srivastava, S. Enigmatic Role of Exosomes in Breast Cancer Progression and Therapy. Life Sci. 2021, 120210. https://doi.org/10.1016/j.lfs.2021.120210.
  95. Sriram, A.; Tangirala, S.; Atmakuri, S.; Hoque, S.; Modani, S.; Srivastava, S.; Mahajan, S.; Maji, I.; Kumar, R.; Khatri, D. Budding Multi-Matrix Technology—a Retrospective Approach, Deep Insights, and Future Perspectives. AAPS PharmSciTech 2021, 22 (8), 1–40.
  96. Gugulothu, D.; Choudhary, S. K.; Khatri, D. K. The Extraction and Investigation of Polysaccharide Mucilages for Use as Excipients in Drug Delivery Systems and Their Application for Developing Floating Tablets of Silymarin. J. Excipients Food Chem. 2021, 12 (4), 70–86.
  97. Iyer, A.; Jyothi, V. G. S. S.; Agrawal, A.; Khatri, D. K.; Srivastava, S.; Singh, S. B.; Madan, J. Does Skin Permeation Kinetics Influence Efficacy of Topical Dermal Drug Delivery System?: Assessment, Prediction, Utilization, and Integration of Chitosan Biomacromolecule for Augmenting Topical Dermal Drug Delivery in Skin. J. Adv. Pharm. Technol. Res. 2021, 12 (4), 345.
  98. Tomar, D.; Singh, P. K.; Hoque, S.; Modani, S.; Sriram, A.; Kumar, R.; Madan, J.; Khatri, D.; Dua, K. Amorphous Systems for Delivery of Nutraceuticals: Challenges Opportunities. Crit. Rev. Food Sci. Nutr. 2020, 1–18. https://doi.org/10.1080/10408398.2020.1836607.
  99. Parul Grover, Lovekesh Mehta, Tanveer Naved, Sandeep Kumar, Gorav Monga, Identification and Characterization of in vitro Metabolites of Belinostat by Rat Liver Microsomes using Ultra Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry. Ind. J. Pharm. Edu. Res. 2021, 56, 1-9.
  100. Parul Grover, Lovekesh Mehta, Tanveer Naved, Sandeep Kumar, Identification and Characterization of in vitro Metabolites of Ibrutinib by Rat Liver Microsomes using Ultra Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry. Ind. J. Pharm. Sci. 2021-Accepted
  101. Neeraj Kumar. Listing of drug delivery device patents in USFDA’s Orange Book: What the patent drafters could learn from Lantus® soloSTAR® device lawsuit. Expert Opinion on Therapeutic Patents, 2021; 31, 1075-1077. DOI: 10.1080/13543776.2021.1994946.
  102. Neeraj Kumar and Shishu Goindi. “Development, characterization and preclinical evaluation of nanosized liposomes of itraconazole: 32 full factorial design to estimate the relationship between formulation components.” Journal of Drug Delivery Science and Technology, 2021; 66, 102785. DOI: 10.1016/j.jddst.2021.102785.
  103. Neeraj Kumar and Shishu Goindi. “Development and optimization of itraconazole loaded solid lipid nanoparticles for topical administration using high shear homogenization process by design of experiments: In vitro, ex vivo and in vivo evaluation.” AAPS PharmSciTech, 2021; (in press). DOI: 10.1208/s12249-021-02118-3
  104. Neeraj Kumar, Balraj Saini and Rajwinder Kaur. “A non-toxic ionic liquid composition for delivery of biological macromolecular anions across skin barrier.” Pharmaceutical Patent Analyst, 2021; 10, 191-194. DOI: 10.4155/ppa-2021-0012.
  105. Balraj Saini, Rajwinder Kaur and Neeraj Kumar. “Natural Products as Sources of Multitarget Compounds: Advances in the Development of Ferulic Acid as Multitarget Therapeutic”. Current Topics in Medicinal Chemistry (accepted).