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Publications in 2016

Publications are the primary method for reporting and long-term documentation of the research conducted at the NIPER-Hyderabad. Here the list of publications published in year wise...


  1. Nagula Shankaraiah, Chetna Jadala, Shalini Nekkanti, Kishna Ram Senwar, Narayana Nagesh, Shweta Shrivastava, VGM Naidu, Manda Sathish, Ahmed Kamal; Design and synthesis of C3-tethered 1, 2, 3-triazolo-β-carboline derivatives: Anticancer activity, DNA-binding ability, viscosity and molecular modeling studies. Bioorganic chemistry, 2016, 64, 42-50.
  2. Lalita Guntuku, VGM Naidu, Veera G Yerra.; Mitochondrial Dysfunction in Gliomas: Pharmacotherapeutic Potential of Natural Compounds. Current neuropharmacology 2016, 14(6),567-583
  3. Kishna Ram Senwar, T Srinivasa Reddy, Dinesh Thummuri, Pankaj Sharma, VGM Naidu, Gannoju Srinivasulu, Nagula Shankaraiah.; Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3′-methoxy-4′-(2-amino-2-oxoethoxy)-benzylidene) indolin-2-ones as potential antitumour agents. European journal of medicinal chemistry, 2016, 118, 34-46.
  4. Kishna Ram Senwar, T Srinivasa Reddy, Dinesh Thummuri, Pankaj Sharma, Suresh K Bharghava, VGM Naidu, Nagula Shankaraiah.;Design and synthesis of 4′-O-alkylamino-tethered-benzylideneindolin-2-ones as potent cytotoxic and apoptosis inducing agents. Bioorganic & Medicinal Chemistry Letters, 2016, 26(16), 4061-4069.
  5. Pankaj Sharma, Dinesh Thummuri, T Srinivasa Reddy, Kishna Ram Senwar, VGM Naidu, Gannoju Srinivasulu, Suresh K Bharghava, Nagula Shankaraiah.; New (E)-1-alkyl-1H-benzo [d] imidazol-2-yl) methylene) indolin-2-ones: Synthesis, in vitro cytotoxicity evaluation and apoptosis inducing studies. European Journal of Medicinal Chemistry, 2016 , 122, 584-600.
  6. Pankaj Sharma, T Srinivasa Reddy, Dinesh Thummuri, Kishna Ram Senwar, Niggula Praveen Kumar, VGM Naidu, Suresh K Bhargava, Nagula Shankaraiah.; Synthesis and biological evaluation of new benzimidazole-thiazolidinedione hybrids as potential cytotoxic and apoptosis inducing agents. European Journal of Medicinal Chemistry, 2016, 124, 608-621.
  7. Uttam B. Karale, Saradhi Kalari, Jala Shivakumar, Vitthal B. Makane, Dattatraya A. Babar, Ritesh P. Thakare, Bathini Nagendra Babu, Sidharth Chopra, Haridas B. Rode*.; Ligand-free Pd-catalysed decarboxylative arylation of imidazo[1,2-a]pyridine-3-carboxylic acids with aryl bromides. RSC Adv., 2016, 6, 65095–65104.
  8. K. N. Visweswara Sastry, Sunitha Rani Routhu, Soma Gupta Datta, Narayana Nagesh, Bathini Nagendra Babu, Jagadeesh Babu Nanubolu, C. Ganesh Kumar, Ram Awatar Maurya*, Ahmed Kamal*.; Synthesis, DNA binding affinity and anticancer activity of novel 4H-benzo[g][1,2,3]triazolo[5,1-c] [1,4]oxazocines. Org. Biomol. Chem., 2016, 14, 9294–9305.
  9. Atulya Nagarsenkar, Lalita Guntuku, Sravanthi Devi Guggilapu, Danthi Bai K., Srinivasulu Gannoju, V.G.M. Naidu,**, Nagendra Babu Bathini.*; Synthesis and apoptosis inducing studies of triazole linked 3-benzylidene isatin derivatives. European Journal of Medicinal Chemistry, 2016, 124, 782-793.
  10. Rahul B, Chavan, Rajesh Thipparaboina, Dinesh Kumar and Nalini R. Shastri.; Co amorphous systems: A product development perspective. Int. J. Pharm, 2016, 515, 403–415.
  11. Anjali Jain, Konda Reddy Kunduru, Arijit Basu, Boaz Mizrahi, Abraham J. Domb, Wahid Khan.; Injectable formulations of poly(lactic acid) and its copolymers in clinical use. Adv. Drug Deliv. Rev, 2016, 107, 213–227.
  12. Arijit Basu, Konda Reddy Kunduru, Sindhu Doppalapudi, Abraham J. Domb, Wahid Khan, Poly(lactic acid) based hydrogels. Adv. Drug Deliv. Rev, 2016, 107, 2016, 192–205.
  13. Anjali Jain, Sindhu Doppalapudi, Abraham J. Domb, Wahid Khan.; Tacrolimus and curcumin co-loaded liposphere gel: Synergistic combination towards management of psoriasis. J. Control. Release, 2016, 243, 132–145.
  14. Sameer S. Katiyar, Eameema Muntimadugu, Towseef Amin Rafeeqi, Abraham J. Domb, Wahid Khan.; Co-delivery of rapamycin and piperine loaded polymeric nanoparticles for breast cancer treatment. Drug Deliv., 2016, 23, 2608-2616.
  15. Diana E. Ickowicz, Ester Abtew, Wahid Khan, Ludmila Golovanevski, Carolyn F. Weiniger,Abraham J. Domb.; Poly(ester-anhydride) for controlled delivery of hydrophilic drugs. J. Bioact. Compat. Pol., 2016, 31, 127-139.
  16. Sindhu Doppalapudi, Anjali Jain, Upendra Bulbake, Wahid Khan.; Nanotherapeutics: Emerging trends in management of psoriasis. Pharm Nanotechnol. 2016, 4, 1-17.
  17. Rohan Ghadi, Eameema Muntimadugu, A.J. Domb, Wahid Khan, Xiang Zhang., Synthetic biodegradable medical polymer: Polyanhydrides, Science and Principles of Biodegradable and Bioresorbable Medical Polymers Eds: Xiang Zhang. Elsevier Publications 2016, 153-187.
  18. Naveen Chella, Bhaskar Daravath, Dinesh Kumar, Rama Rao Tadikonda.; Formulation and Pharmacokinetic Evaluation of Polymeric Dispersions Containing Valsartan. European Journal of Drug Metabolism and Pharmacokinetics. 2016, 41(5), 517–526.
  19. P Komirishetti, A Areti, R Gogoi, R Sistla, A Kumar.; PARP inhibition reveals a potential mechanism to promote neuroprotection and for the treatment of neuropathic pain. Neural Regeneration Research, 2016, 11 (10), 1545-1548.
  20. S Reddemma, VG Yerra, P Komirishetty, A Areti, A Kumar.; Fisetin Imparts Neuroprotection in Experimental Diabetic Neuropathy by Modulating Nrf2 and NF-κB Pathways. Cellular and Molecular Neurobiology, 2016, 36 (6), 883-892.
  21. N. Satheeshkumar, David Paul, A. Lingesh.; Liquid Chromatography-Mass Spectrometry (LC-MS) - Approaches to Adulterant Detection in Herbal Products. Tsay, H.-S., Shyur, L.-F., Agrawal, D.C., Wu, Y.-C., Wang, S.-Y. (Eds.) Medicinal Plants - Recent Advances in Research and Development. Springer International Publishing, Switzerland , 2016, 73-95.
  22. N. Satheeshkumar, R.S. K Vijayan, A. Lingesh, S. Santhikumar and Ch. Vishnuvardhan.; Spices: Potential Therapeutics for Alzheimer’s Disease. M.M. Essa et al. (eds.), The Benefits of Natural Products for Neurodegenerative Diseases, Advances in Neurobiology. Springer International Publishing Switzerland, 2016, 12, 57-78.
  23. Chiguru Vishnuvardhan , Debasish Swain , Roshan Borkar , S. Gananadhamu , R. Srinivas , N. Satheeshkumar.; Study of forced degradation behaviour of brinzolamide using LC-ESI- Q-TOF and in silico toxicity prediction. Chromatographia, 2016, 79, 1293.
  24. Senwar, K. R.; Sharma, P.; Reddy, T. S.; Thummuri, D.; Naidu, V.G.M.; Shankaraiah, N.; Design, synthesis and apoptosis inducing novel (Z)-3-(3'-methoxy-4'-(2-amino-2-oxoethoxy)-benzylidene)indolin-2-ones as potential cytotoxic agents. Eur. J. Med. Chem., 2016, 118, 34–46.
  25. Shankaraiah, N.; Sharma, P.; Pedapati, S.; Nekkanti, S.; Srinivasulu, V.; Kumar, N. P.; Kamal, A.; Synthesis of Novel C3-Linked β-Carboline-Pyridine Derivatives Employing Khronke Reaction: DNA-binding Ability and Molecular Modeling Studies. Lett. in Drug Design & Discovery, 2016, 13, 335–342.
  26. Manish Kumar Jeengar.; Sri Vishnu Kiran Rompicharla.; Shweta Shrivastava.; Naveen Chella.; Nalini R Shastri.; VGM Naidu.; Ramakrishna Sistla.; Emu oil based nano-emulgel for topical delivery of curcumin. International journal of pharmaceutics, 2016, 506, 222-236.
  27. Rajesh Kumar Gurram.; Suchithra Gandra.; Nalini R Shastri.; Design and optimization of disintegrating pellets of MCC by non-aqueous extrusion process using statistical tools. Eur J Pharm Sci., 2016, 84, 146–156.
  28. Amitha Thakur.; Rajesh Thipparaboina.; Dinesh Kumar.; Kodukula Sai Gouthami.; Nalini R Shastri.; Crystal Engineered Albendazole with Improved Dissolution and Material Attributes. CrystEngComm, 2016, 18, 1489-1494.
  29. Rajesh Thipparaboina.; Dinesh Kumar.; Rahul B. Chavan.; Nalini R. Shastri.; Multidrug co-crystals: towards the development of effective therapeutic hybrids. Drug Discov Today, 2016, 21, 481–490.
  30. Supriya Dattatray Jitkar.; Rajesh Thipparaboina.; Rahul B Chavan.; Nalini R. Shastri.; Spherical Agglomeration of Platy Crystals: Curious Case of Etodolac. Cryst. Growth Des, 2016, 16, 4034–4042.
  31. Rajesh Thipparaboina.; Sudhir Mittapalli.; Sowjanya Thatikonda.; Ashwini Nangia.; V. G. M. Naidu.; and Nalini R Shastri.; Syringic Acid: Structural Elucidation and Co-Crystallization. Cryst. Growth Des., 2016, 16, 4679–4687.
  32. Rahul B. Chavan.; Rajesh Thipparaboina.; Dinesh Kumar.; Nalini R. Shastri.; Evaluation of the inhibitory potential of HPMC, PVP and HPC polymers on nucleation and crystal growth. RSC Adv., 2016, 6, 77569.
  33. Prinesh N. Patel.; Pradipbhai D. Kalariya.; Swamy C.V.; Gananadhamu S.; Srinivas R.; Quantitation of acotiamide in rat plasma by UHPLC-Q-TOF-MS: method development, validation and application to pharmacokinetics. Biomed Chromatogr, 2016, 30, 363-368.
  34. Debasish Swain.; Prinesh N Patel.; Gangam Nagaraj.; Kona S Srinivas.; Mahesh Sharma.; Prabha Garg.; Gananadhamu Samanthula.; Liquid Chromatographic Method Development for Forced Degradation Products of Dabigatran Etexilate: Characterisation and In Silico Toxicity Evaluation. Chromatographia, 2016, 79, 169-178.
  35. Debasish Swain.; Gananadhamu Samanthula.; Shweta Bhagat.; P.V. Bharatam.; Venkatakrishna Akula.; Barij N. Sinha.; Characterization of forced degradation products and in silico toxicity prediction of Sofosbuvir: A novel HCV NS5B polymerase inhibitor. J. Pharm. Biomed. Anal., 2016, 120, 352-363.
  36. Talluri* M.V.N.K.; Kalariya, P.D.; Dharavath. S,; Automated statistical experimental design approach for rapid separation of coenzyme Q10 and its biotechnological process related impurities using UPLC and UPLC/APCI/MS. J Sep Sci., 2016 39(18), 3528-35.
  37. Mahamuni. B. S, Jajula. A, Awasthi A, Kalariya. P. D, Talluri, M.V.N.K.; Selective separation and characterisation of stress degradationproducts and process impurities of prucalopride succinate by LC-QTOF-MS/MS. J. Pharm. Biomed. Anal, 2016, 125, 219–228.
  38. Uttam B. Karalea, Saradhi Kalaria, Jala Shivakumar, Vitthal B. Makanea, Dattatraya A. Babara, Ritesh P. Thakare, Bathini Nagendra Babu, Sidharth Chopra, Haridas B. Rode,; Ligand-free Pd-catalysed decarboxylative arylation of Imidazo[1,2-a]pyridine-3-carboxylic acids with Aryl bromides. RSC Advances, 2016 , 69.
  39. Atulya N., S. K. Prajapti, Sravanthi Devi G., Swetha B., Sudha S. K., Ramesh U., Bathini Nagendra Babu,; Investigation of triazole-linked indole and oxindole glycoconjugates as potential anticancer agents: novel Akt/PKB signaling pathway inhibitors. RSC, MedChemComm, 2016 7, 646.
  40. S. K. Prajapti, Atulya N., Sravanthi Devi G., Gupta, K., Lingesh A, Manish Kumar J., V. G. M. Naidu, Bathini Nagendra Babu,; Synthesis and biological evaluation of oxindole linked indolyl-pyrimidine derivatives as potential cytotoxic agents. Bioorganic & Medicinal Chemistry Letters, 201626, 3024.
  41. Sravanthi Devi G., S. K. Prajapti, Atulya N., G. Lalita, V.G.M. Naidu and Bathini Nagendra Babu.; MoO2Cl2 catalyzed efficient synthesis of functionalized 3,4-dihydropyrimidin-2(1H)-ones / thiones and polyhydroquinolines: Recyclability, Fluoroscence and Biological studies. RSC New Journal Chemistry, 2016, 40, 838.
  42. Sravanthi Devi G, S. K. Prajapti, Atulya N, Keshav K. G., Bathini Nagendra Babu.; Indium(III) Chloride Catalyzed Synthesis of 5-Substituted 1H-Tetrazoles from Oximes and Sodium Azide. Synlett, 2016, 27, 1241.
  43. Bandaru, S.; Alvala, M.; Akka, J.; Sagurthi, S. R.; Nayarisseri, A.; Singh, S. K.; Mundluru, H. P., Identification of Small Molecule as a High Affinity beta2 Agonist Irrespectively Targeting Wild and Mutated (Thr164Ile) beta 2 Adrenergic Receptor in the Treatment of Bronchial Asthma. Current pharmaceutical design, 2016.
  44. Narva, S.; Chitti, S.; Bala, B. R.; Alvala, M.; Jain, N.; Kondapalli, V. G.; Synthesis and biological evaluation of pyrrolo[2,3-b]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA. European journal of medicinal chemistry, 2016, 114, 220-31.
  45. Muntimadugu, E.; Dhommati, R, Jain, A.; Challa, V.G.S.; Shaheen, M.; Khan, W.; Intranasal delivery of nanoparticle encapsulated tarenflurbil: A potential brain targeting strategy for Alzheimer’s disease. Eur. J. Pharm. Sci. 2016, 92, 224-234.
  46. Muntimadugu, E.; Kumar, R.; Saladi, S.; Rafeeqi, T.A.; Khan, W.; CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel. Colloids Surf., B. 2016, 143, 532-546.
  47. Doppalapudi, S.; Jain A.; Domb, A.J.; Khan, W.; Biodegradable polymers for targeted delivery of anticancer drugs; Expet Opin. Drug Deliv. 2016, 13(6) 891-909.
  48. Singh, I.; Swami, R.; Pooja, D.; Jeengar, M.K.; Khan, W.; Ramakrishna, S.; Lactoferrin Bioconjugated Solid Lipid Nanoparticles: A New Drug Delivery System for Potential Brain Targeting. J. Drug Target. 2016, 24(3), 212-23.
  49. Singh, I.; Swami, R.; Khan, W.; Ramakrishna, S.; Chapter 11, Lymphatic System: A Prospective Area for Advanced Targeting of Particulate Drug Carriers. Handbook of Immunological Properties of Engineered Nanomaterials. World Scientific Publishing, 2016, 2, 363-398.
  50. Basu, A.; Farah, S.; Kunduru K.R.; Doppalapudi, S.; Khan W.; Domb A.J.; Chapter 8, Polyurethanes for controlled drug delivery, Advances in Polyurethane Biomaterials, Eds: Cooper & Guan. 1st Edition, Elsevier Publications, 2016, 217-246.
  51. Ghadi, R.; Jain, A.; Khan, W.; Domb, A. J.; Chapter 12, Microparticulate polymers and hydrogels for wound healing, Wound Healing Biomaterials - Volume 2: Functional Biomaterials Eds: Magnus Agren. Elsevier Publications, 2016, 203-225.
  52. Kommineni, N.; Khan, W.; Nanomedicine in global market; Nano Digest, July 2016, 36-41.
  53. Vishnuvardhan Ch, Allakonda L, Srinivas R, Satheeshkumar N.; Forced degradation study of racecadotril: Effect of co-solvent, characterization of degradation products by UHPLC-Q-TOF-MS/MS, NMR and cytotoxicity assay. Journal of Pharmaceutical and Biomedical Analysis, 2016, 128, 9–17.
  54. Chiguru Vishnuvardhan , Saibaba Baikadi, Roshan M Borkar, R. Srinivas, N. Satheeshkumar.; In vivo metabolic investigation of silodosin using UHPLC–QTOF–MS/MS and in silico toxicological screening of its metabolites. Journal of Mass Spectrometry, 2016.
  55. Syed Safiullah Ghori, Md Ikram Ahmed, Md. Arifuddin, Md Shoaibuddin Khateeb.; Evaluation of analgesic and anti-inflammatory activities of formulation containing camphor, menthol and thymol. International Journal of Pharmacy and Pharmaceutical Sciences, 2016, 8 (1), 271-274.
  56. K. C. Rajanna., Aneesa Ferdose., K. Rajender Reddy., Md. Arifuddin., M. Moaazzam Ali.; Transition metal ions as catalysts for efficient formylation of hydrocarbons with Vilsmeier -Haack reagents: Kinetics and mechanism. Journal of Solution Chemistry, 2016, 45(3), 371-394.
  57. Safiullah SG, Shazia S, Fouzia F, Ummara H, Arifuddin M, and Tasneem M.; Isolation of Phytosterols from the methanolic extracrt of leaves of Ficus Dalhousiae Miq. RJPBCS, 2016, 7(4), 847-854.
  58. Nekkanti, S.; Veeramani, K.; Kumar, N. P.; Kamal, A.; Shankaraiah, N.; Microwave-assisted direct oxidative synthesis of α-ketoamides from aryl methyl ketones and amines by a water soluble Cu(I)-complex. Green Chem., 2016, 18, 3439–3447.
  59. Krishna, N. H.; Saraswati, A. P.; Sathish, M.; Shankaraiah, N.; Kamal, A.; Silver-Catalyzed Domino Aza-Annulation/Diels-Alder Cyclization of 2-ene-yne Anilines: A Facile One-Pot Access to Carbazole, Dihydrocarbazole and Tetrahydrocarbazole Frameworks. Chem. Comm. 2016, 52, 4581–4584.
  60. Sathish, M.; Chetna, J.; Krishna, N. H.; Shankaraiah, N.; Alarifi, A.; Kamal, A.; Iron-Mediated Concise One-Pot Synthesis of 3, 5-Diarylpyridines from beta-Nitrostyrenes. J. Org. Chem., 2016, 81, 2159–2165.
  61. Nekkanti, S.; Kumar, N. P.; Sharma, P.; Kamal, A.; Nachtigall, F. M.; Forero-Doria, O.; Santos, L. S.; Shankaraiah, N.; TBAI/TBHP-Catalyzed [3+2] cycloaddition / oxidation / aromatization cascade and online ESI-MS mechanistic studies: Synthesis of pyrrolo[2,1-a]isoquinolines and indolizino[8,7-b]indoles. RSC Adv., 2016, 6, 2671–2677.
  62. D. Ravikumar Reddy, Amit Khurana, Swarna Bale, Ramu Ravirala, V. Samba Siva Reddy, M. Mohan Kumar, Chandraiah Godugu.; Natural Flavonoids Silymarin and Quercetin Improve the Brain Distribution of Co-administered P-gp Substrate Drugs. SpringerPlus, 2016.
  63. Swarna Bale, Amit Khurana, Mandip Singh and Chandraiah Godugu.; Overview on Therapeutic Applications of Microparticle Drug Delivery System. Critical Reviews in Therapeutic Drug Carrier Systems, 2016.
  64. Chandraiah Godugu, Ravi Doddapaneni, Stephen H Safe, Mandip Singh.; Novel Diindolylmethane derivatives based NLC formulations to improve the oral Bioavailability and anticancer effects in Triple Negative Breast Cancer. European Journal of Pharmaceutics and Biopharmaceutics, 2016.
  65. Srikrishna D, Chandraiah Godugu, Dubey PK.; A Review on Pharmacological properties of Coumarins. 2016.
  66. Chandraiah Godugu, Singh M.; AlgiMatrix™-Based 3D Cell Culture System as an In Vitro Tumor Model: An Important Tool in Cancer Research. Methods Mol Biol. 2016, 1379,117-28.
  67. Tiruveedi VL, Bale S, Khurana A, Chandraiah Godugu.; Tankyrase as a Novel Molecular Target in Cancer and Fibrotic Diseases. Curr Drug Targets. 2016.
  68. Chandraiah Godugu, Doddapaneni R, Patel AR, Singh R, Mercer R, Singh M.; Novel Gefitinib Formulation with Improved Oral Bioavailability in Treatment of A431 Skin Carcinoma. Pharm Res, 2016, 33(1):137-54.
  69. Sunitha Sampathi, Rakesh Achanta, Pankaj Tiriya, Sonia Gera, P Sravanthi Reddy, Venu Talla.; “Formulation and Evaluation of Carvedilol Loaded Lactide Nanoparticles: An Appraisal to Anti-Hypertensive and Anti-Inflammatory Therapy. Advanced Science, Engineering and Medicine, 2016, 8(7):503-514.
  70. Sunitha S, Sonia Gera, Srikanth H, Ashok Z.; “Synthesis and evaluation of olmesartan medoxomil complex with SBE7 β-CD for enhanced dissolution and bioavailability”. International Journal of Pharmacy and Pharmaceutical Sciences, 8(1), 2016.
  71. Jeengar, M., Shrivastava, S., Mouli Veeravalli, S., Naidu, V., and Sistla, R. (2016). Amelioration of FCA induced arthritis on topical application of curcumin in combination with emu oil. Nutrition, 2016, 32: 955-964.
  72. Kulhari, H., Pooja, D., Shrivastava, S., Kuncha, M., Naidu, V., and Bansal, V. et al. (2016). Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer. Sci. Rep., 2016, 6:23179.
  73. Areti, A., Yerra, V., Komirishetty, P., and Kumar, A., Potential Therapeutic Benefits of Maintaining Mitochondrial Health in Peripheral Neuropathies. Current Neuropharmacology, 2016, 14(6):593-609.
  74. Komirishetty, P.; Areti, A.; Sistla, R.; Kumar, A.; Morin Mitigates Chronic Constriction Injury (CCI)-Induced Peripheral Neuropathy by Inhibiting Oxidative Stress Induced PARP Over-Activation and Neuroinflammation. Neurochem Res., 2016, 41(8), 2029-2042.
  75. Komirishetty, P.; Areti, A.; Yerra, V.; PK, R.; Sharma, S.; Gogoi, R. et al.; PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy. Life Sciences. 2016, 150, 50-60.
  76. Kumar. A.; Mitochondrial Dysfunction & Neurological Disorders. Current Neuropharmacology. 2016 14(6), 565-566.
  77. Yerra. V., Gundu. C., Bachewal, P., Kumar. A.; Autophagy: The missing link in diabetic neuropathy?. Medical Hypotheses. 2016 86, 120-128.
  78. Siresha Bathina.; Nanduri Srinivas.; Undurti N.Das.; BDNF protects pancreatic β cells (RIN5F) against cytotoxic action of alloxan, streptozotocin, doxorubicin and benzo(a)pyrene in vitro; Metabolism, 2016, 65 (5), 667-684.
  79. Digwal C S, Yadav U, Sakla A P, Ramya P V S, Aaghaz S, Kamal A; VOSO4 catalyzed highly efficient synthesis of benzimidazoles, benzothiazoles, and quinoxalines. Tet. Lett., 57, 2016, 4012.
  80. Reddy V G, Reddy T S, Nayak V L, Prasad B, Reddy A P, Ravikumar A, Taj S, Kamal A; Design, synthesis and biological evaluation of N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1,3-diphenyl-1H-pyrazole-4-carboxamides as CDK1/Cdc2 inhibitors. Eur. J. Med. Chem., 2016,122, 164.
  81. Yellaiah T, Manasa K L, Sathish M, Alarifi A, Kamal A; Phenyliodonium Diacetate Mediated One-Pot Synthesis of Benzimidazoles and Quinazolinones from Benzylamines. Chemistry Select, 2016, 1, 2895.
  82. Nayak V L, Nagaseshadri B, Vishnuvardhan M V P S, Kamal A; Investigation of the apoptotic pathway induced by benzimidazole–oxindole conjugates against human breast cancer cells MCF-7. Bioorg. Med. Chem. Lett., 2016, 26, 3313.
  83. Kamal A, Bajee S, Nayak V L, Rao A V S, Nagaraju B, Reddy Ch.R, Kapure J S, Alarifi A; Synthesis and biological evaluation of arylcinnamide linked combretastatin-A4 hybrids as tubulin polymerization inhibitors and apoptosis inducing agents. Bioorg. Med. Chem. Lett., 2016, 26, 2957.
  84. Srikanth P S, Nayak V L, Babu K S, Kumar G B, Ravikumar A, Kamal A; 2-Anilino-3-Aroylquinolines as Potent Tubulin Polymerization Inhibitors. ChemMedChem, 2016, 11, 2050.
  85. Kamal A, Nayak V L, Nagesh N, Vishnuvardhan M V P S, Reddy N V S; Benzo[b]furan derivatives induces apoptosis by targeting the PI3K/Akt/mTOR signaling pathway in human breast cancer cells, Bioorganic Chemistry, 2016, 66, 124.
  86. Borkar R, Bhandi M M, Dubey A P, Reddy V G, Komirishetty P, Nandekar P P, Sangamwar A T, Kamal A, Banerjee S K, Ragampeta S; An Evaluation of the CYP2D6 and CYP3A4 inhibition potential of metoprolol metabolites and their contribution to drug-drug and drug-herb interaction by LC-ESI/MS/MS. Biomedical Chromatography, 2016, 30, 1556.
  87. Kamal, A; Mahesh, R; Nayak, V.L; Babu, K.S; Kumar, G.B; Shaik, A.B; Kapure, J.S; Alarifi, A; Discovery of pyrrolospirooxindole derivatives as novel cyclin dependent kinase 4 (CDK4) inhibitors by catalyst-free, green approach. Eur. J. Med. Chem., 2016, 108, 476.
  88. Kamal A, Shaik B, Nayak V L, Rao A V S, Nagaraju B, Reddy Ch R, Kapure J S, Alarifi A; Synthesis and Biological Evaluation of Arylcinnamide linked Combretastatin-A4 hybrids as Tubulin Polymerization Inhibitors and Apoptosis Inducing Agents. Bioorg. Med. Chem. Lett, 2016, 26, 2957.
  89. Kamal A, Srikanth P S, Vishnuvardhan M V P S, Kumar G B, Babu K S, Hussaini S M A, Kapure J S, Alarifi A. Combretastatin linked 1,3,4-oxadiazole conjugates as a Potent Tubulin Polymerization inhibitors. Bioorganic Chemistry, 2016, 65, 126.
  90. Suja T D, Divya K V L, Nayak V L, Ravikumar A, Kamal A; Copper-catalyzed three-component synthesis of aminonaphthoquinone–sulfonylamidine conjugates and in vitro evaluation of their antiproliferative activity. Bioorg. Med. Chem. Lett., 2016, 26, 2072.