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Publications in 2014

Publications are the primary method for reporting and long-term documentation of the research conducted at the NIPER-Hyderabad. Here the list of publications published in year wise...


  1. Kamal, A.; Rao, A. S.; Nayak, V. L.; Reddy, N. S.; Swapna, K.; Ramakrishna, G.; Alvala, M., Synthesis and biological evaluation of imidazo [1, 5-a] pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway. Organic & biomolecular chemistry 2014, 12 (48), 9864-9880.
  2. Shrivastava, S.; Kulkarni, P.; Thummuri, D.; Jeengar, M. K.; Naidu, V.; Alvala, M.; Redddy, G. B.; Ramakrishna, S., Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells. Apoptosis 2014, 1-17.
  3. Anjali Jain, L. Sailaja Duvvuri, Shady Farah, Nurit Beyth, Abraham J. Domb, Wahid Khan, Antimicrobial Polymers, Adv. Healthc. Mater. 2014 3(12), 1969-85.
  4. Indu Singh, Rajan Swami, Wahid Khan, and S. Ramakrishna, Lymphatic system: a prospective area for advanced targeting of particulate drug carriers, Expet Opin. Drug Deliv. 2014 11(2), 211-229.
  5. Sindhu Doppalapudi, Anjali Jain, Wahid Khan, Abraham J. Domb, Biodegradable Polymers – An overview, Polym. Adv. Technol. 2014 25, (5) 427–435.
  6. Jacob Sosna, Ehud Havivi, Wahid Khan, Liat Appelbaum, Abraham Nyska and Abraham J. Domb, Computed tomography of Lipiodol loaded biodegradable pasty polymer for implant visualization, Contrast Media Mol. I. 2014 9(3), 246–251.
  7. Wahid Khan,Venu Gopala Swami Challa, Robert Langer, and Abraham J. Domb, Chapter 1, Biodegradable polymers for focal delivery systems, In Book- Advances in Delivery Science and Technology- Focal Controlled Drug Delivery 2014, 3-32.
  8. Wahid Khan, Eameema Muntimadugu, Michael Jaffe and Abraham J. Domb, Chapter 2, Implantable Medical Devices, In Book- Advances in Delivery Science and Technology- Focal Controlled Drug Delivery 2014 33-60.
  9. Rajan Swami, Dinesh Kumar, Wahid Khan, Sistla Ramakrishna, Nalini Shastri, Chapter 5, Polymer drug conjugate in focal drug delivery, In Book- Advances in Delivery Science and Technology- Focal Controlled Drug Delivery, 2014, 117-148.
  10. Muntimadugu Eameema, Lakshmi Sailaja Duvvuri, Wahid Khan, and Abraham J. Domb, Chapter-10, Polyanhydrides, In Book- Natural and Synthetic Biomedical Polymers 2014, 181-192.
  11. Sheeba Qureshi, Wahid Khan, Michael Perez-Davidi, Ervin I Weiss and Abraham J. Domb, Chapter 13, Local Delivery systems to the oral cavity, In Book- Advances in Delivery Science and Technology- Focal Controlled Drug Delivery 2014, 285-304.
  12. Wahid Khan, Rajesh Thipparaboina, Shady Farah, Judah Z. Weinberger, Abraham J. Domb, Chapter- 18, Drug eluting stents, In Book- Advances in Delivery Science and Technology- Focal Controlled Drug Delivery 2014 387-404.
  13. Indu Singh, Wahid Khan, Ramakrishna Sistla, Chapter 20, Delivery systems for lymphatic targeting, In Book- Advances in Delivery Science and Technology- Focal Controlled Drug Delivery 2014, 429-458.
  14. Wahid Khan, Venu Gopala Swami Challa, Rajendra P. Pawar, Meir Nyska, Yaron S. Brin, Abraham J. Domb, Chapter 21, Antibiotics delivery for treating bone infections, In Book- Advances in Delivery Science and Technology- Focal Controlled Drug Delivery 2014, 459-472.
  15. Anjali Jain, V Amarendar Reddy, Eameema Muntimadugu, Wahid Khan, Nanotechnology in vaccine delivery, Curr. Trends in Pharm. Sci. 2014 2(1),17-27.
  16. Shankaraiah, N.; Nekkanti, S.; Chudasama, K. J.; Senwar, K. R.; Sharma, P.; Jeengar, M. K.; Naidu, V. G. M.; Srinivasulu, V.; Kamal, A.; Design, Synthesis and Anticancer Evaluation of Tetrahydro-ß-Carboline-hydantoin Hybrids; Bioorg. Med. Chem. Lett. 2014, 24, 5413–5417
  17. Vishnuvardhan Chiguru,; Srinivas Ragampeta,; SatheeshKumar, N.; Development and validation of a UPLC method for screening potentially counterfeit anti-hypertensive drugs using design of experiment. Analytical Methods, 2014, 6, 4610-4616.
  18. Satheeshkumar, N.; Shantikumar, S.; Srinivas, R. Pioglitazone: A Review of Analytical Methods. Journal of Pharmaceutical Analysis, 2014; 4 (5), 295–302
  19. Satheeshkumar, N.; Spandana, V.; Shantikumar, S.; Srinivas, R. Experimental design approach to optimize stability indicating LC method for the determination of Naftopidil in its bulk and tablet dosage form. Journal of Young Pharmacist, 2014; 6(1):1-7
  20. Shanti Kumar Saladi, Sreekanth Gutala, Krishnaveni Yadiki, M.V.NarendraKumar and N SatheeshKumar. Design and study of a HPLC method for the simultaneous estimation of two anti-diabetic drugs using statistical approach. Analytical Methods, 2014, 6, 3291-3299. IF: 1.93
  21. Vishnuvardhan, C.; Radhakrishnanand, P.; Navalgund, S.G.; Atcha, K.R.; Satheeshkumar, N., RP-HPLC Method for the Simultaneous Estimation of Eight Cardiovascular Drugs. Chromatographia, 2014, 77(3-4), 265-275.
  22. Satheeshkumar, N.; Pradeepkumar, M.; Shanthikumar, S.; Rao, V. J., Development of Validated Stability Indicating Assay Method for Simultaneous Estimation of Metformin Hydrochloride and Vildagliptin by RP-HPLC. Drug Res (Stuttg), 2014, 64(3), 124-129.
  23. Nimbarte, V. D.; Murtuza, H.; Phaniraj, S.; Shrivastava, S.; Naidu, V. G. M.; Satheeshkumar, N.; Atcha, K.R., Design, synthesis and biological evaluation of 4-(1-(4(sulphanilamide)phenyl)-3-(methyl)-1H-pyrazol-5-yl)dine urea and N-acyl derivatives as a soluble epoxide hydrolase inhibitors. Med Chem Res, 2014, 23(5), 2178-2197.
  24. Shantikumar,S.; Sreekanth, G.; SurendraNath, KV.; JaferValli, S.; Satheeshkumar, N., Compatibility study between Sitagliptin and pharmaceutical excipients used in solid dosage forms. Journal of Thermal Analysis and Calorimetry, 2014, 115(3), 2423-2428.
  25. Satheeshkumar, N.; Nisha, N., Phytomedicines as Potential Inhibitors of ß Amyloid Aggregation: Significance to Alzheimer's Disease. Chin. J. Nat. Med, 2014, 12(11): 836-853
  26. Pradipbhai D. Kalariya, Murali V. N. Kumar Talluri*, Vinay D. Gaitonde, Prashant S. Devrukhakar, Ragampeta Srinivas, Quality by design: A systematic and rapid liquid Chromatography and mass spectrometry method for eprosartan mesylate and its related impurities using a superficially porous particle column. Journal of Separation Science, 2014 37, 2160-2171.
  27. Pradipbhai D. Kalariya, M. V. N. Kumar Talluri*, Ragampeta Srinivas, Experimental Design Approach for Selective Separation of Vilazodone HCl and its degradants by LC-PDA and Characterization of major degradants by LC/QTOF-MS/MS, Chromatographia, 2014 77, 1299-1313.
  28. M.V.N. Kumar Talluri*, Naveen Reddy Kandimalla, Raju Bandu, Divya Chundi, Ramesh Marupakab, Ragampeta Srinivasa, Selective separation, detection of zotepine and mass spectral characterization of degradants by LC–MS/MS/QTOF, Journal of Pharmaceutical Analysis 2014;4(2):107–116.
  29. Kamal, A.; Satish, M.; Srinivasulu, V.; Chetna, J.; Shekar, K. C.; Tangella, Y.; Shankaraiah, N.; Asymmetric Michael addition of ketones to nitroolefines by employing pyrrolidinyl-oxazole-carboxamides as new efficient organocatalysts; Org. Biomol. Chem. 2014, 12, 8008–8018
  30. Kamal, A.;Reddy, T. S.; Polepalli, S.; Shalini, N.; Reddy, V. G.; Rao, A. V. S.; Jain, N.; Shankaraiah, N;Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors; Bioorg. Med. Chem. 2014, 22, 5466–5475
  31. Kamal, A.; Srinivasulu, V.; Nayak, V. L.; Sathish, M.; Shankaraiah, N.; Bagul, C.; Reddy, N. V. S.; Rangaraj, N.; Nagesh, N;Design and synthesis of C3-pyrazole/chalcone linked ß-carboline hybrids: Antitopoisomerase I, DNA interactive and apoptosis inducing anticancer agents; ChemMedChem. 2014, 9, 2084–2098
  32. Kamal, A.; Reddy, T. S.; Polepalli, S.; Paidakula, S.; Srinivasulu, V.; Reddy, V. G.; Jain, N.; Shankaraiah, N; Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors; Bioorg. Med. Chem. Lett. 2014, 24, 3356–3360
  33. S Sandireddy, Yerra Veera Ganesh, Aparna Areti, Prasanth Komirishetti, Ashutosh Kumar; Neuroinflammation and Oxidative Stress in Diabetic Neuropathy: Futuristic Strategies Based on these Targets; International Journal of Endocrinology, Special issue entitled “Oxidative Stress and Inflammation in Diabetic Complications”. 2014
  34. Ajit Vikram, Durga Nand Tripathi, Ashutosh Kumar, Sandeep Singh;“Oxidative stress and Inflammation in Diabetic Complications”, International Journal of Endocrinology. 2014
  35. Dinesh Thummuri, Manish Kumar Jeengar, Shweta Shrivastava, Aparna Areti, Veera Ganesh Yerra, Samyuktha Yamjala, Prashanth Komirishetty, V.G.M. Naidu, Ashutosh Kumar, Ramakrishna Sistla; Boswellia ovalifoliolata abrogates ROS mediated NF-?B activation,causes apoptosis and chemosensitization in Triple Negative Breast Cancer cells; Environmental Toxicology and Pharmacology. 2014, 38(1), 58–70
  36. Santosh Kumar Prajapti, Atulya Nagarsenkar, Bathini Nagendra Babu; An efficient synthesis of 5-substituted 1H-tetrazoles via B(C6F5)3 catalyzed [3+2] cycloaddition of nitriles and sodium azide; Tetrahedron Letters, 2014, 55, 3507.
  37. Santosh Kumar Prajapti, Atulya Nagarsenkar, Bathini Nagendra Babu; Tris(pentafluorophenyl)borane catalyzed acylation of alcohols, phenols, amines, and thiophenols under solvent-free condition; Tetrahedron Letters, 2014, 55, 1784.
  38. Pradipbhai D. Kalariya, B. Raju, Roshan M. Borkar, Deepak Namdev, S. Gananadhamu, Prajwal P. Nandekar, Abhay T. Sangamwar, R. Srinivas. Characterization of forced degradation products of ketorolac tromethamine using LC/ESI/Q/TOF/MS/MS and in silico toxicity prediction, J. Mass Spectrom. 2014, 49, 380–391.
  39. Kamal, A.; Srinivasulu, V.; Sathish, M.; Tangella, Y.; Nayak, V. L.; Rao M. P. N.; Shankaraiah, N.; Nagesh, N. Pd-Catalyzed Aryl C-H Activation and Tandem ortho-Hydroxylation/Alkoxylation of 2-aryl benzimidazoles: Cytotoxicity and DNA-Binding Studies; Asian J. Org. Chem. 2014, 3, 68–76
  40. Uppuluri Venkata Mallavadhania, Nagi Reddy Vangaa, Manish Kumar Jeengar, V.G.M. Naidu.Synthesis of novel ring-A fused hybrids of oleanolic acid with capabilities to arrest cell cycle and induce apoptosis in breast cancer cells. European Journal of Medicinal Chemistry, 2014, 74, 398-404.
  41. Areti A, Yerra VG, Naidu VGM, Kumar A. Oxidative stress and Nerve Damage: Role in Chemotherapy Induced Peripheral Neuropathy. Redox Biology. 2014, 2, 289-295.
  42. S. Naveen Kumar, C. H. N. S. Sai Pavan Kumar, E. Srihari, Sravani Kancharla,b Kolupula Srinivas, Shweta Shrivastava, V. G. M. Naidu* and V. Jayathirtha Rao First total synthesis of fuzanins C, D and their analogues as anticancer agents RSC Adv., 2014, 16, 7845-8514.
  43. Hitesh Kulhari, Deep Pooja, Shweta Shrivastava, Naidu V.G.M, Ramakrishna Sistla, Peptide conjugated polymeric nanoparticles as a carrier for targeted delivery of docetaxel. Colloids and Surfaces B: Biointerfaces, 2014, 117, 166-173.
  44. Deepak, N.; Roshan, M. B.; Raju, B.; Pradipbhai, D. K.; Vinodkumar, T. R.; Gananadhamu, S.; Srinivas, R. Identi?cation of forced degradation products of Tamsulosin using liquid chromatography/electrospray ionization tandem mass spectrometry. J. Pharm. Biomed. Anal. 2014, 88, 245-255.
  45. Prinesh N. Patel.; Gananadhamu, S.; Veeraraghavan S.; Rambabu A.; Kanthi Kiran V. S. Varanasi.; Swaroop Kumar V.V.S. Validated LC-MS/MS method for simultaneous determination of Dasatinib and Sitagliptin in rat plasma and its application to pharmacokinetic study, Anal. Methods. 2014, 6, 433-439.
  46. Sunitha, S.; Jitendra, W.; Sujatha, D.; Santhosh Kumar, M. Iran.;Design and Evaluation of Hydrogel-Thickened Microemulsion for Topical Delivery of Minoxidil; J. Pharma. Sci. 2013, 9, 1- 14.
  47. Satheeshkumar, N.; Naveen, G., A Stability Indicating RP-HPLC Method For Ambrisentan-An Endothelin Receptor Antagonist;. J Chrom Sci, 2014; 52(8):894-8.
  48. Satheeshkumar, N.; Nisha, N., Phytomedicines as Potential Inhibitors of ß Amyloid Aggregation: Significance to Alzheimer's Disease.; Chin. J. Nat. Med, 2014, 12(11): 836-853.
  49. Priyanka, P.; Sujatha, D.; Pushpa kumara, B.; Charisma, V.V.L.;Evaluation of aqueous extract of Murraya koenigii in unilateral renal ischemia reperfusion injury in rats; Indian . J. Pharmacol. 2014, 46, 171-175.
  50. Mahesh Kumar, G.; Srikanth, Ch.; Sujatha, D,; Sunitha, S.;Formulation and Characterization of Ambroxol Hydrochloride Loaded Ethyl Cellulose Microparticles for Sustained Release; J. Biomater. Tissue. Eng. 2014, 4, 669-678.
  51. Swetha, K.; Sujatha, D.; Sunitha, S.; Priyanka, P.; Gopichand, Ch.;Ethanolic extract of Aloe vera ameliorates sciatic nerve ligation induced neuropathic pain; Ancient Science of Life. 2014, 33, 208-215.
  52. Bandaru, S.; Marri, V. K.; Akka, J.; Alvala, M.; Mundluru, H. P., Association of Transforming Growth Factor-Beta 1 Promoter Variant-509 C/T with Bronchial Asthma in South Indian Population. Inflammation 2014, 1-6.
  53. Jeengar MK, Shrivastava S, Nair K, Singareddy SR, Putcha UK, Talluri MV, Naidu VG, Sistla R. Improvement of bioavailability and anti-inflammatory potential of curcumin in combination with emu oil. Inflammation. 2014, 37(6):2139-55.
  54. Uppuluri Venkata Mallavadhani, Chakka Vara Prasad, Shweta Shrivastava, VGM Naidu. Synthesis and anticancer activity of some novel 5, 6-fused hybrids of juglone based 1, 4- naphthoquinones. European journal of medicinal chemistry, 2014, 83:84-91
  55. Vadla Ramesh, Boddu Ananda Rao, Pankaj Sharma, B Swarna, Dinesh Thummuri, Kolupula Srinivas, VGM Naidu*, Vaidya Jayathirtha Rao. Synthesis and biological evaluation of new rhodanine analogues bearing 2-chloroquinoline and benzo [h] quinoline scaffolds as anticancer agents. European journal of medicinal chemistry, 2014, ;83:569-80
  56. Bandari Uma Mahesh, Shweta Shrivastava, Rajeswara Rao Pragada, V.G.M. Naidu*, Ramakrishna Sistla. Antioxidant and hepatoprotective effect of Boswellia ovalifoliolata bark extracts. Chinese Journal of Natural Medicine. 2014, 12 (9):663-71.
  57. VGM Naidu*, S Shrivastava, MK Jeengar, PS Kumar, VS Reddy, SS Reddy Cardamonin suppresses the proliferation of gastric cancer cells by promoting ß-catenin degradation. Abstract published in supplementary issue of European Journal of Cancer, 2014 50, S9
  58. S Shrivastava, MK Jeengar, D Thummuri, VGM Naidu*. Piperlongumine inhibits growth potential of gastric cancer cells by targeting PI3K/Akt/mTOR signaling pathway. Abstract Published in supplementary issue of European Journal of Cancer, 2014 50, S9.
  59. Swarna.B, Dinesh.Thummuri, Lavanya Bindu Sree.A, V.G.M. Naidu*, Interplay of RANKL in Oxidative Stress Induced Bone Loss. Current Trends in Pharmaceutical Sciences, 2014, 2: 12-16
  60. V G M Naidu, Atmakur H, Katragadda SB, Devabakthuni B, Kota A, S CK, Kuncha M, M V P S VV, Kulkarni P, Janaswamy MR, Sistla R. Antioxidant, hepatoprotective and cytotoxic effects of icetexanes isolated from stem-bark of Premna tomentosa. Phytomedicine. 2014, 15;21(4):497-505.
  61. Kuncha M, Naidu VG, Sahu BD, Gadepalli SG, Sistla R. Curcumin potentiates the anti-arthritic effect of prednisolone in Freund's complete adjuvant-induced arthritic rats. Journal of Pharmacy & Pharmacology. 2014, 66(1):133-44.
  62. Vijaykumar D. Nimbarte, Hadianawala Murtuza, Sahishna Phaniraj, Shweta Shrivastava, V. G. M. Naidu, N. Satheesh Kumar, Krishnam Raju Atcha. Design, synthesis and biological evaluation of 4-(1-(4(sulphanilamide)phenyl)-3-(methyl)-1H-pyrazol-5- yl)dine urea and N-acyl derivatives as a soluble epoxide hydrolase inhibitors. Medicinal Chemistry Research, 2014, 23: 2178-2197
  63. Chella Naveen, Narra Nataraj, Tadikonda Rama Rao. Preparation and Characterization of Liquisolid Compacts for Improved Dissolution of Telmisartan. Journal of drug delivery, 2014, Article ID 692793, 10 pages
  64. Samanthula, G.; Shrigod, V. V.; Patel, P. N. Validated Stability-Indicating Assay Method for Simultaneous Determination of Aceclofenac and Thiocolchicoside using RP-HPLC, Drug Research. 2014; 64(08): 429-435.