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Animal House @ NIPER Hyderabad


Research in bio-medical science is required for improvement of the quality of human life. This improvement stems in part from progress in ameliorating human disease and disability, in part from advances in animal health and veterinary medicine, and in part from the enlargement of our understanding of complex and intricately connected biological systems of human and animal physiology and its disorders. Besides that, work with living animals is vital to continue progress in many areas of clinical and basic research. Though there are alternatives in the form of cell and tissue culture, lower animal study or computer simulation, the use of whole animal is irreplaceable. The mission of the NIPER, Hyderabad animal facility is to provide animals of required specification for research projects of this Institute as well as to carry out a continuous research on laboratory animals.

Starting from the unicellular organisms, a variety of animal species contribute each year to medical breakthroughs that save millions of human lives each year. Through research on these animals, scientists have discovered cure and prevention for a number of human and animal ailments. However, with the humane approach to the treatment of lives of the animals and development of alternative techniques, the wastage of animal lives has been remarkably prevented. But this rational use of animals is not enough. It is to be remembered, the fundamental principle is that animals must not be subjected to avoidable distress or discomfort. The other major responsibility of this facility is to ensure the persuasion of 3Rs (Replacement, Reduction and Refinement) of animal experimentation and the ethical principles of animal use are followed as per CPCSEA guidelines.

Animal house CPCSEA Registration

The animal house facility has been registered by CPCSEA and awarded the Registration No. 1548/PO/RE/a/CPCSEA.

Institutional Animal Ethics Committee

All the experiments involving animals are approved by the IAEC which is constituted by CPCSEA. The IAEC meetings are held regularly to obtain ethical clearance for use of animals in academics and research. The facility maintains all relevant records to ensure compliance to the approvals granted by the committee and progress under each approved protocol is put up for review by IAEC regularly in each meeting.

Dr. Uday kumar Putcha
Scientist – F,National Instituete of Nutrition
CPCSEA Main Nominee putchaaaudaykumar@yahoo.com
Dr.K. Rajender Rao
Scientist – D ,National Institute of Nutrition
CPCSEA Link Nominee rkrajander@yahoo.com
Dr. Ramavat Ravindar Naik
Technical Office
National Institute of Nutrition
National Centre for Laboratory Animal Sciences
Scientist From outside the Institute appointed by CPCSEA rnramavat@gmail.com
MS. Dhavala Gouri Satyaprabha Non Scientific Socially Aware Nominee appointed by CPCSEA gppp221@gmail.com
Associate Professor
National Institute of Pharmaceutical Education and Research (NIPER)
Chairman nalini@niperhyd.ac.in
Dr. T. Venu
National Institute of Pharmaceutical Education and Research (NIPER)
Member Secretary venu@niperhyd.ac.in
In-charge of Animal House facility
National Institute of Pharmaceutical Education and Research (NIPER)
In-charge of Animal House facility and Veterinarian Doctor nandkumar@niperhyd.ac.in

Pharmacological and Toxicological Screening facilities

Our Institute is currently equipped to conduct the following screening procedures using various animal models.
  • Acute, sub-acute and chronic toxicity studies of drugs
  • Screening of analgesic, anti-inflammatory, anti-pyretic and anti-arthritic drugs
  • Screening of anti cancer drugs
  • Screening of hepato-protective agents
  • Screening of anti-diabetic drugs
  • Screening of anti-ulcer drugs
  • Screening of psoriasis model
  • Screening of Pulmonary Fibrosis model
  • Screening of anti-parkinson agents
  • Screening of pharmacokinetic (PK) study
  • Screening of xenograft nude mice model

Details of Animals housed in the facility

Species Strain
Mice Swiss Albino
Rat Albino Wistar

We procure animals from the CPCSEA approved vendors.

Infrastructural facilities

The structure of our animal facility includes
  • Quarantine room
  • Experimental room
  • Animal store room
  • Procedure room
  • Wash area
  • Bedding/Feed storage room
  • Autoclave room

Instrumentation facility

In vivo Pharmacological/toxicological screening facility includes rota rod, actophotometer, swimming test apparatus, y-maze, elevated plus maze, Hebb-william maze, eddy’s hot plate, analgesiometer and plethysmograph for behavioural screening. Basic equipments such as pH meter, Deep freezer, homogenizer, centrifuge, microscope, calorimeter etc are also available.

Animal care

The animal house is air conditioned and well protected against environment contamination. The animal house team comprises 3 staff members including a Scientist In-charge of Animal House facility, Technical assistant and animal house attendant. The support staff ensures that every part of animal care including feeding, watering, restraining, cage cleaning, record keeping and ordering of animals, feeds and bedding materials.

Veterinary care

Veterinarian carries out regular health monitoring of all animals to ensure that they are free from contagious diseases. Necropsy and autopsy of suspected contagious/infectious animals are performed by the veterinarian and prophylactic measures are implemented.

Waste disposal

The bio-waste disposal procedure is followed as per CPCSEA guidelines.